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Peter L. Pedersen

Professor
Biological Chemistry
Johns Hopkins Medicine
United States of America

Biography

Dr. Peter Pedersen is a professor of biological chemistry and oncology at the Johns Hopkins University School of Medicine. His research focuses on cell energetics, its molecular and chemical basis, and relationship to both disease and to the discovery of new therapies. He studies both mitochondrial and glycolytic processes at the tissue, cell, and molecular level, as well as the relationship of these processes to cancer and heart disease, the two leading causes of death in the U.S., with the ultimate goal of developing new therapies. Dr. Pedersen graduated from the University of Tulsa with a B.S. in Chemistry. He earned a Ph.D. in chemistry from the University of Arkansas. He proceeded to the Johns Hopkins University School of Medicine to do a postdoctoral fellowship in the Department of Physiological Chemistry. Dr. Pedersen has been an active educator during his tenure, instructing such courses as Preclinical Sciences, Biochemistry and Metabolism to the medical students in the School of Medicine. In doing so, he has received countless awards recognizing his important role in the preclinical coursework. He has been a prolific author, having published over 366 articles with abstracts and 241 without abstracts. He was born in Muskogee, Oklahoma as the son of a strawberry farmer and a chemistry teacher.

Research Interest

Cell energetics

Publications

  • Ko YH, Verhoeven HA, Lee MJ, Corbin DJ, Vogl TJ, Pedersen PL. "A translational study ‘case report' on the small molecule ‘energy blocker' 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside." J Bioenerg Biomembr. 2012 Feb;44(1):163-70.

  • Queirós O, Preto A, Pacheco A, Pinheiro C, Azevedo-Silva J, Moreira R, Pedro M, Ko YH, Pedersen PL, Baltazar F, Casal M. "Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate." J Bioenerg Biomembr. 2012 Feb;44(1):141-53.

  • Dyląg M, Lis P, Niedźwiecka K, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S. "3-Bromopyruvate: a novel antifungal agent against the human pathogen Cryptococcus neoformans." Biochem Biophys Res Commun. 2013 May;3;434(2):322-7.

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